The article aims to present a scientific justification of new scientific prospects for the formation of a progressive political economy – a space political economy with an appropriate cosmoplanetary worldview. The scientific foundations of a systemic socio-economic and interdisciplinary nature allow us to move from the political determination of the economy to the synthesis of scientific knowledge. The author's evolutionary-historical and systemic approaches draw attention not only to the thinking of Aristotle, who separates economics from chrematistics and shows the primacy of higher social goals over lower ones, but also to the thinking of modern global thinkers who assert the term cosmoglobalism. The historical analysis of the social development of capitalism presented by Marx, Engels, Lenin and other researchers, as well as the implementation of the Marxist worldview in the USSR and the experience of building socialism do not save the country from the crisis. The analysis of the world system of capitalism with developed overconsumption, a violation of cosmological principles detrimental to nature and society, contains dangerous threats to the life of all mankind. In connection with the emergence of new scientific opportunities through the formation of integral knowledge by science, the task of transition to scientific and rational management of social development - the space age is put forward. Attention is drawn to the need to organize a global system of information production of a